The German suffered a dead leg in the win over Sheffield United last weekend.
"It is still painful with contact so we took him out of half of the training today when we did some small-sided games and the possession games," manager Thomas Tuchel told reporters.
"We didn't risk it today and we will not risk it tomorrow. We could have risked it but the decision stands. Hopefully, he will recover and be back on Monday [to face Newcastle]."