Hull have lost the past four games.
But Bruce said: "The one thing I could never question of this team since I've been here is the resilience of them.
"They're desperate to stay in the Premier League. The effort and endeavour of them was there for all to see on Tuesday. We were unfortunate. We need a big result and, hopefully, it comes against Spurs.
"One win gives you a huge boost and it's a big opportunity at home.
"Our home record has been good, picking up a lot of points, so let's hope we can do it again."
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