Hull have experimented with different attacking combinations but after Saturday's 3-3 draw with West Ham, Brown is happy with his latest choice of front two - Altidore and Craig Fagan.
Brown said: "They have formed a relationship with each other. Hopefully that partnership will blossom. Jozy just needs a goal. His match fitness is better than ever, having played a full game against Stoke and then two full games for the USA.."
Brown admitted that he had a dilemma on his hands over whether to start with Altidore in the last game against West Ham - as there were many unanswered questions over the player, who may not have been ready following international duty.
The Hull boss said: "Could he last the full game? Did he want to start the game? But the fact the USA played in Europe, as opposed to America, meant it was almost an internal flight that he had - coming back from Denmark to England. So there were no questions about fatigue or jet lag and he wanted to play and I think he showed that."