The pacey England attacker has been missing in recent games, but he has resumed light training with the club.
Howe is hoping that he will be able to call on the player as soon as this weekend, where they face a key clash against Huddersfield.
The Cherries boss also admitted he is keeping an eye on the league table, as he does not want Bournemouth involved in the relegation scrap in the last few weeks of the season.
"He's done some light training this week and been back on the grass for first time and he's looked pretty good," said Howe of Wilson during his pre-match press conference.
"We're in a similar position to last week, we'll have to pick and choose the right moment for him to come back. I'm going to have to consult with Callum and the physios to see how he feels [before Huddersfield.]
"We recognise now that games are running out for us and we're in a position where our safety isn't secured and we're losing distance with the teams above us.
"There's still a gap but until you're away from that area [relegation] but you have to look at it game by game. We're looking upwards at the teams we want to catch but we have to win games.
"We're absolutely desperate to do it and I think it's important we do it quickly, we want that momentum back in our performances."