Wilson's first goal in almost a year, following a serious knee injury which ended his promising start to last season, secured a 1-0 victory over West Brom.
"It was a big moment for him," said Howe. "You could see that with the celebration with all his team-mates.
"It's been a long road for Callum. I think it's everything for him when that's what you do, you score goals. You don't feel like you are considered back to being fit until you are scoring goals again.
"You have to remember that when he suffered the injury he was probably at the peak of his career. He was looking red hot for us and then he's had to watch the team doing well in the Premier League without him. So it was a very good day for him individually."