Former Manchester United goalkeeper Mark Bosnich says their top four hopes will be over should they lose to Chelsea next week.
United's goalless draw at home with Wolves just before the winter break leaves them six points behind the Blues.
Bosnich, who also played for Chelsea, told Sky Sports: “I don't think it's win or bust but you could lean towards it being lose or bust.
“I think it's a must not lose. The gap will be a little bit far to catch up if they lose, but not win or bust no.
“They're not far off and Chelsea will be looking to this with Tottenham breathing down their necks and they're at home.
"They both had a week's break so it will be a very important game for both sides.
“For Chelsea and Frank Lampard they will be looking to get breathing space between them and the chasing sides."