The midfielder, signed from Lille this summer, was dispossessed after lingering on the ball to long in the midfield. Liverpool capitalised decisively as Mohamed Salah eventually finished off the resulting breakaway with a neat finish.
"It's a learning curve, but we shouldn't have got to that stage in the first place," said Hughton speaking about Bissouma's Anfield error on the club's website.
"But overall I am pleased; he has trained very well, he's young and still getting used to the way we play.
"He's a talented player and he'll improve in each game."