Setien enjoyed a winning debut yesterday with a 1-0 victory over Granada.
Busquets said afterwards, "What has changed in this match compared to the previous ones with Ernesto Valverde? It is not a question of comparing. Each coach has his style and his way of conceiving football.
"You will see what (Quique) Setién asks of us. We are not going to reveal it to you. We are delighted with what Ernesto (Valverde) has done and we are delighted with Setién."