Barca are in Naples for Tuesday night's Champions League round 16 first-leg clash with Napoli.
“We have to expect the best version of Napoli, in these games teams give their all," said Setien in his pre-game press conference.
“Tomorrow will be a difficult game for both sides, it will be played face-to-face. We have seen what they are capable of, and not only in the Champions League.
“They have overcome rivals with greater resources and tomorrow they will produce a great display."
“He's a player that I view with great affection and he has developed greatly. I am pleased for him.
“I hope that tomorrow he will not play with all of his qualities. But I am very pleased to see him score [against Brescia], not only is he a great player but also a very humble boy and a beautiful person."