Iniesta was part of the Barca side which started with a loss and a draw when Guardiola took over at The Nou Camp in 2008.
He told the Daily Mail: "Pep knows how to adapt and he'll adapt to the Premier League. He has made sure to get people on his staff who are going to help him do that. Mikel Arteta is only going to speed up that process.
And they have strengthened the squad very well over the summer. City are competitive in all departments.
"I know Nolito very well because he was with me at Barcelona and he's a teammate with Spain. He's made a great start. I hope that everything goes well for him and that he continues to play as well as he has so far. "And David Silva was already there. I have admired him throughout my career. He is exceptional."