Griezmann wasn't seen until the 91st minute against his former club for Tuesday night's 2-2 draw.
Asked to comment, Simeone repeated his immediate post-match reaction: "I have no words."
It was then put to Simeone if Griezmann was wrong to leave, he replied: "I don't want to be disrespectful to the answer. At the moment we are playing a lot in this season finale and that point is not important for us today."
One journalist also asked, "As a driver of the Atlético truck, have you ever had to apologise to a player for taking him out alone in the final minutes?"
Simeone replied, “I don't drive a truck, I drive a team of footballers who work for a major club like Atleti. In our team, three minutes are decisive, we lost a Champions League final in three minutes and for me they are very important."