Last season saw Arsenal triumph 3-1 over Spurs and the anticipation of experiencing a similar scene has Arteta relishing the afternoon.
He said: “I think our supporters will be crucial. If they are able to create the atmosphere they did last year - which I'm sure they will - the team will be flying because it is just so helpful.
“I can't wait to see the atmosphere, I am so excited about it," he added. “We experienced an incredible game and atmosphere last time we played them at home and I encourage everyone to do the same.
“The belief and emotion and the passion they put in really helps the team get what we want. It transforms the emotion, the players' implication and level of confidence. It is a driving force, so hopefully we'll experience that again."
Before kick-off, the now-familiar sound of Louis Dunford's The Angel will ring around the stadium.
Speaking about his feelings for the song, he said: “I get emotional. It is unique, it is from a local guy that has huge feelings for our football club and has shown it in a very natural way, and the timing clicked.
“It's not something we created - it was something that happened naturally. It was like a huge wave and the supporters bought into it. They feel it and you can sense it."