The Gunners are set to face the MLS select in the annual summer friendly in San Jose on July 28.
The former Chelsea star, who has tormented Arsene Wenger's side on numerous occasions in the past, has been named in the All-Stars squad and Chambers acknowledges it is a great opportunity to learn from one of the game's greats.
"He is probably the player I'm looking forward to playing the most.
"He just always scores important goals. The way he plays, obviously he is strong and is a big character. To match up with players like that is what you want to do and who you want to play against.
"That for me will be a great experience to play against him.
"He was always in the right place at the right time and the way he plays, he's got a great finish on him as well and he is strong. He has the whole package which makes him such a handful."