Cazorla has not featured for the Arsenal first team since 2016, after suffering a serious Achilles injury. Many operations later, Cazorla is in line for a return in 2019.
But it is unclear if the 33-year-old will ever reach the same levels as before, given the length of time he has been absent from the game.
Wenger spoke about the matter with the Evening Standardand said the following:
"Yes, of course. We miss him a lot. I never spoke about it in the press conferences, or not many times, as he was not the subject of the day but we have missed him a lot in our game. He is an exceptional football player and it is very sad what happened to him, and very sad for Arsenal as well.
"I have not seen him since the League Cup final because he has gone back to [Spain to] make his rehab. We leave him there. But the last news I heard is that he is doing very well, so I hope that certainly he will come back before the end of the season and we can make a check-up of where he stands.
"Can he play again in the Premier League? I don't know, I have to see how he responds to his injury."