Wilshere, 18, is regarded as among the best of his generation and impressed during the weekend's Emirates Cup.
Asked about being worried by an early England call, Wenger told arsenal.com: "No. At the end of the day when you are a good football player you have to deal with that. Theo Walcott was at the World Cup at 17 years of age. He had not played one game in the Premier League and it didn't kill him. To play at the top level you have to deal with these kind of situations."
He added: "At 18 years of age you need a bit of patience. I believe he is stronger than last year, physically. The few months he played at Bolton has given him something. He will be used at the Club, of course."