Victory will guarantee Champions League qualification for the Gunners.
Arteta said, "We try to approach every game emotionally as well the best way, with moments and people that can describe what a game means better than I do, or in a different way than I do. We always try to find the right way to get the players in the right mindset to play the game that they have to play that day.
"Whatever we do it's always [inside] or closed, and we will continue to do that.
"It's different because the history of north London, we all know about it, and what it means to our fans. After that it's a football pitch with a lot of noise and a crowd that will be excited to support their team, and we'll have our fans as well for sure one hundred percent behind the team.
"The winning factor is always the best feeling! It's different obviously as a player and manager, but in every occasion, it's not just about winning, it's about how you win those matches and the experience that you go through throughout the 90 minutes, especially when you play at home in front of your crowd."
On claims of qualifying for the Champions League in England being like winning a title, Arteta added: "I have heard that quote now many times from many different managers and I think Arsene (Wenger) was the first one who said it because he could probably see what was happening in this league and the difficulty of achieving that.
"It was the way he described it and it was the way that he felt, and I feel that for the club it would be extremely important."
Need a VPN? Or seeking to switch? Then support Tribal Football by clicking here to sign up with our official partners NordVPN. Not only will you receive the best VPN experience, but also great discounts by signing up via Tribal Football. Thanks for your support!