But the star striker thinks this weekend's victory - Villa's first at Old Trafford for 26 years - is the most precious.
He told Villa's website: "I think this win is the biggest - especially when you look at the history of the fixture.
"Not many teams go to Old Trafford and win either so we're obviously very happy with that. We want to build on it.
"It's nice to think I've created a bit of history with the goal too. Hopefully it doesn't take another 26 years to see another. Who knows? I might still be playing then.
"The defeat last season played a part because we were hurt. It was in the back of our minds.
"I thought we did really well in that particular game and should have got something out of it. To come back and win, we can take a lot of pride out of it."
Agbonlahor was also glowing in his praise for star provider Ashley Young, who produced an exquisite cross for the goal.
"Everyone knows what Ashley is capable of and he was showing that with the crosses he was putting in.
"I knew when he got the ball exactly what he was going to do and then it was up to me to make that run into the box and make sure I made contact.
"Luckily it went on my head and I nodded home. I tried to hold the ball up in the build-up, give it to him and then let him do what he does best. He did it brilliantly and I managed to connect."