Wigan Athletic chairman Dave Whelan has confirmed Emile Heskey will be out for six weeks with a metatarsal injury.
Whelan told Sky Sports News: "It's been a fantastic week, but a disappointing end. He has cracked a metatarsal in his foot. We had it confirmed last night.
"It's not a serious one, but it is still six weeks and I think he will definitely miss the first England game.
"It is bad luck, we are all aware of that. We were shocked yesterday. He just jumped up in the air and came down on his ankle.
"To do that is such bad luck, bad for Wigan, bad for England."