The Hammers are in Toronto for Thursday night's match against a Major League Soccer All-Star team.
Asked whether such a match would be possible midway through a Premier League season, as is the case with the MLS, the England cap was positive.
"I think it could be, yes," Ashton said. "Coming over here I was quite surprised at how big an event it is and all the media surrounding it.
"So if it's such a big deal over here I can't see why something like that can't be really good over in England.
"It's a great event and we're definitely looking forward to it."
The MLS All-Star squad is selected by voting from fans, the media, team head coaches and general managers.
Ashton claimed he saw no reason why the best players in England could not join together for a similar event.
"It's a great concept, especially for all the fans to see all their best players in one team, so I don't see why not," he said.
"I don't know if it would ever happen, though. That's another matter."