The Hammers midfielder will return from suspension.
Zola said: "We will have Scott Parker back this weekend which is very positive. He is a very talented and key player for us. Everyone knows what he gives us in terms of his passion and commitment.
"It will be good to have him back but we have to win as a team and everyone will have to produce a performance.
"We all know how important the Wigan game is. We will be ready. We have four days to prepare and we will be doing it in the best way possible. None of us are pleased about this performance. We can only react, play better and win the game on Saturday."