Anelka has a lengthy ban hanging over him due to his 'quenelle' gesture controversy.
Asked if Anelka would play against Aston Villa, Mel said: "He has a 99 per cent chance, yes.
"I have already spoken with Anelka and the only thing he wants to do is help the team beat Aston Villa.
"I think he showed against Everton that he has absolutely no problem.
"The most important thing for me as the head coach is his performance on the pitch.
"Stephane Sessegnon (who is injured) is the only player who is not available - everyone else is available and Anelka, for me, played well against Everton."
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