Wenger feels it is important to "take a distance" from Saturday's disappointment, where a scrappy goal from former Arsenal trainee Colin Kazim-Richards inflicted a first FA Cup defeat by lower-league opposition on his side.
He said: "We have to analyse the game. We lost to a team who had one shot at goal, it is not like we have not touched the ball in the Blackburn game.
"Football is about skill, intelligence and some things as well are a bit unpredictable."
Wenger stressed his team must take no notice of the negative headlines and broken cannon motifs if they are to progress over two legs against the Bundesliga giants.
"We know well what is going on here. What is important is to forget what people say and focus on our strengths," he said.
"We play for Arsenal in the last 16 of the Champions league, we have qualified for a long, long time.
"What is important is not what people say it is what happens on the pitch.
"We live in a democracy of experts and opinions, but we have to live with that and cope with that and show we have the mental strength to deal with any opinion. There are a lot of experts who are not necessarily always right."