As the debate rages on as to who should and should not play for Start Pearce's Team GB, Wenger has thrown in his opinion that the likes of Theo Walcott, Kieran Gibbs, Alex Oxlade-Chamberlain, Jack Wilshere and Aaron Ramsey would be overworked if they competed at London 2012.
"If you look at the organisation of the whole summer, it makes life impossible for the clubs and the players especially," he said.
"At some stage you have to decide how far you can go medically for the players to play so many games under so much pressure.
"I would say there is already no real break because of the European Championship (not in Ramsey's case) and the Olympic tournament for me is not a real football tournament, for me the Olympics is for track and field basically."
He added: "The competition (Olympics) is after the European Championship. The Euros finish on 1st July, we start the championship (Premier League) on 15th August, we start pre-season training on 4th or 5th July, that means we will not have the players after the Euros.
"If we are losing them as well to the Olympic Games I think I will have to sign a licence to practise all over the summer because we will not have players. It cannot work.
"The Olympics finish in mid-August, so imagine a player who has played the Euros and Olympic Games. You think you can use him after that? It's impossible. I don't know what people think when they organise these competitions."