Villarreal boss Marcelino expects Mateo Musacchio to join Tottenham.
The two clubs are locked in talks over a fee for the Argentina defender.
Marcelino told local reporters on the weekend: "There is a situation with three parties: the player, the buyer and the club in the middle and, as I said many times, if the club sell an important player, it's because the right conditions are in place.
"Things will change a lot.
"The quality and level (Musacchio has) will make it difficult to find a replacement."
