Aston Villa captain Martin Laursen has suffered a fresh injury setback.
The Danish defender had hoped to be back in contention for the Barclays Premier League clash at Manchester United on April 5.
But the former AC Milan player, sidelined since early January, had a reaction during training and his knee swelled.
Villa manager Martin O'Neill confirmed: "Martin has had a bit of a setback. He was doing fine and then his knee got a bit sore and puffed up a little bit after training.
"Hopefully it will only be a three or four-day setback. But any setback at this stage would be a genuine one simply because of Martin's importance to the team.
"Maybe his enthusiasm was too strong - he was possibly doing too much, too soon. But we will see.
"He may even have been ahead of schedule at one stage - so we just hope it's a minor setback at the moment."