"We showed this season, we play as a team," said Vidic. "It is not just about one man.
"Definitely Wayne Rooney has had a great season. He is unbelievable, one of the best in the world.
"But sometimes big players are missing, and others need to be ready."
Bought for a club record £30.75million in 2008, the Berbatov has struggled to win over his critics, largely due to his relaxed style of play.
"Dimitar had a great game against Bolton on Saturday. He is a great footballer," said Vidic.
"He scored twice himself and can set up goals for other players as well.
"We have a good squad. We just need to believe in ourselves and believe in each other."