The 25-year old Ecuadorian winger has returned for United’s last three matches after suffering a serious ankle injury in September and is beginning to get back to full fitness.
Ferguson says Valencia’s comeback could coincide with the Red Devils’ return to form after two losses in their last three league outings.
“Antonio has showed in the parts of the games he's played so far why we've missed him,” Ferguson told Inside United.
“He is a fantastic footballer. He came on at the right time against Marseille because Nani was starting to wilt a bit after his injury.
“His ability to get to the dead ball line is a big advantage to us and his football brain was there for all to see when he made Javier Hernandez's second goal against Marseille. His pass to Ryan Giggs was fantastic.
“It is a big plus point. Having both Antonio and Nani is a big boost for us.”