Utaka - who is hoping to shake off a hamstring injury - insists that Pompey will be doing everything they can to claim victory.
"It's a derby match, so of course we want to win," the striker told the Pompey website. "We know how important it is for the fans and we want to win it for them. Everyone is really excited about the match and it's one that we can hopefully be victorious in.
"A lot of the squad have never played in this match before and everyone wants to be involved. Cup games are always difficult and you never know what to expect, so we will not be taking Southampton lightly.
"But we're confident that we can do well and progress through to the next round."