The Friulani have only won one game all season against nine-man Milan, as Anzhi held them to a 1-1 home draw in the group opener.
"The atmosphere will certainly be impressive and the lads might not be accustomed to that kind of pressure-cooker atmosphere," said the Coach.
"Still, I think our focus ought to be on Liverpool, who are a great team. After all, atmosphere is all well and good, but the games are played on the pitch.
"Liverpool haven't had the best start to the season, but that is because they are settling in to a new way of playing with a new Coach who did very well at Swansea last year.
"They paid a price for those big changes, but I have to focus on my own squad and what my players can do."