The Welsh winger has missed the past three weeks of action for Spurs because of a hamstring injury but will be back for the weekend's home clash with Stoke City.
Villas-Boas is delighted to have Bale fit again and feels he will make a massive difference to a side already sitting fourth on the table.
"Yes, we have missed him. He is an important player for us. He can make the difference," Villas-Boas said.
"You saw what he did against Liverpool (when Bale scored and provided an assist in the 2-1 win). He was outstanding.
"Players like him can decide a game for you and for us it is a tremendous boost to have him back, no doubt."