Luis Suarez scored twice while Paulinho was sent off in north London as Spurs bowed to another heavy defeat with Villas-Boas describing the performance of the visitors as 'spectacular'.
"It was difficult for us and Liverpool were spectacular today," Villas-Boas told Sky Sports.
"They were really good pressing and couldn't let us play, and deservingly reached half-time 2-0 up.
"Our response came in the second half, but when we lost Paulinho the game was very, very difficult to turn and Liverpool started dominating possession, putting some balls in behind and we struggled.
"I assume the responsibility of the failure. We have to bounce back like we did after Manchester City.
"In the Premier League, things are not going as we expected, as we wanted, and it's normal that the frustration is there from everybody."
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