Spurs have been linked with a move for the 26-year-old Colombian international after Guarin played under Andre Villas-Boas during his time at Porto.
"These are all lies, neither Fredy nor I are looking for new solutions," Marcelo Ferreyra told calciomercato.it. "He wants to improve and win with Inter.
"We know nothing about Tottenham's interest and I think there is nothing.
"Given the bond we have with Villas-Boas, if there was anything we would be the first to know about it.
"I'm not talking with any clubs because Fredy wants to stay at Inter."