Gascoigne's appearance may soothe the mood inside the Stadio Olimpico with a crowd of around 30,000 expected. The former England star has been invited to Rome by Lazio as a guest of honour, 20 years after he joined them from Spurs.
"It is a big thing for both clubs," said Villas-Boas. "He was admired by a generation of football people around the world. He had tremendous class and quality and it is important he will be here."