That means youngsters Yago Falque, Jake Livermore, Andros Townsend and Tom Carroll are likely to be given a chance to impress in what is expected to be a white-hot atmosphere generated by PAOK's fanatical support.
"It's not a case of prioritising a game, it's just (using) what I have got," Redknapp said.
"I couldn't bring players out here, play them on Thursday night and play the same group against Liverpool.
"If I get a few injuries I have no back up. I have nine senior, very, very good players who are injured.
"Some of them have played two international games so I wanted to change the team around. I have done that. I have not been able to use the strong group I have for this first game because they're not fit."