The ex-Manchester City and Arsenal striker was preferred to Jermain Defoe for Tottenham's visit to the Etihad Stadium last week and the 28-year-old, who scored for Togo in their 1-0 win over Morocco on Wednesday, is likely to get the nod again.
"It is an important game for the club," said the Spurs manager. "I suggest to make the most of it, we can use individuals' motivations. That is why we used Adebayor also in the game versus City last week.
"These are things that you have to count on. Last year he scored from the penalty spot and had a good game."