Villas-Boas now hopes the result in Lyon, which set up a last-16 tie against Inter Milan, will inspire his team to victory at Upton Park.
"We've been having some great, great results," the 35-year-old said.
"After Europa League games we've always been good in the Premier League. I think it puts us in a good position to face West Ham.
"I don't think it's a distraction, I think it's an inspiration and I hope it can be exactly that against West Ham."