The 31-year old Spanish striker has signed with the MLS club for the remainder of the 2010 season and de Guzman, who spent two years with Mista at Estadio Riazor, believes the new addition will add plenty to the playing list.
"I had a chance to play with Mista during my time in Spain and I think it will be a great addition to the team," de Guzman told Toronto's official website. "He brings a lot of experience to the team and is exactly what we need up front at the moment. I am very happy to have him join our team.
"I think it will be an interesting experience for him coming from La Liga and playing in the MLS. I will be there to help him out in any way that I can. I can speak Spanish and Martin Saric, Leo Percovich and some of the other guys in the locker room also speak Spanish so I think he will have no problem fitting into a nice position here.
"He had the chance to come here and train with us a few weeks ago so he got the chance see the team and the city and he was very pleased. Once he had seen what it was like here he was very interested in coming over. Now we are looking forward to having him on the pitch with the team."
Mista will not be able to make his Reds debut until July 17 but de Guzman expects him to be a handful for opposition defences when he does take the pitch.
"He is more of a number nine type striker, a man who will hold up the ball and get the team moving forward. That is pretty much what he did at Deportivo when I played with him," de Guzman added.
"I know in his earlier career he played more as a number 10 at Valencia and also at Atletico Madrid, but lately he has been the guy that holds the ball up and makes the intelligent runs behind the defence. He also has a lethal left foot."