Valencia coach Miroslav Djukic has overseen three defeats in their last four games.
Laudrup said: "It is not nice what he is going through now, but it is part of managing a big club.
"It is great to work with the best players, but sometimes if you lose or only draw games it can become a problem.
"They have lost three games so they have problems, so it is nice for us to have this game first."
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