Gerhard Tremmel will take the Dutchman's place with David Cornell coming onto the bench, and Laudrup is backing the pair to step up.
"I have confidence in Gerhard and also in David," he said. "Of course what I need to have is confirmation of how long it will be with Michel, but I have no problem using Gerhard and David.
"It is a very special position on the pitch and Gerhard has not played many games over the last year and a half and suddenly he will have to play a lot and he starts with two easy games at Anfield and against Chelsea at home!"
He added: "There will be changes, a couple of them are obviously enforced, but I don't know yet how many there will be."