Defender Williams criticised Suarez in a section of his book 'My Premier League Diary', accusing the Uruguayan of being a diver and showing contempt toward his fellow professionals.
Laudrup does not believe the furore will affect the Wales captain.
He said: "We know all about Luis Suarez - and Ashley Williams certainly seems to know about him.
"The comments are not something that surprised me because nothing surprises me in football.
"There have been lots of comments about Suarez, not only from Swansea but lots of other clubs.
"But there is a referee on the pitch and three other officials and they have to manage the game. The important thing is for our players to keep inside the rules and I am 100% sure they will and we will try to win this game.
"But I have no problem with Ashley Williams playing against Luis Suarez, no problem at all."