Mourinho has shuffled his pack in the competition so far this season and is likely to make changes to the side which beat Crystal Palace 2-1 on Saturday.
Poyet said: "Look, I don't think it's going to be a weak Chelsea, I don't. I'm expecting a very strong one.
"Now, we can analyse position by position: [Cesar] Azpilicueta or Ashley Cole - what do you prefer? [Frank] Lampard or Ramires - what do you prefer? [Michael] Essien or [John Obi] Mikel - which do you prefer? [Demba] Ba or [Fernando] Torres? We can go to every position.
"I don't think there are going to be 11 new players from the weekend, I don't. If there is, well let's see if we can take advantage, but I am not expecting too many new faces."
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