After victory over Peterborough United, O'Neill was delighted to be rewarded with what promises to be a fiery local derby with Boro at the Stadium of Light in three weeks' time.
"The last few supporters in the ground let out a big roar when the draw was made," O'Neill said.
"It will be one that we look forward to. It's a great tie for both sets of supporters and we are at home so we will see if we can make that count.
"The Cup is important to this club. We haven't done well in it recently but I will try and put that right."