The Dutchman joined Fenerbahce on a season's loan earlier this month, and scored his first goal for the Turkish side in their 4-1 win over Alanyaspor on Sunday.
When asked about the 23-year-old's goal, Pochettino said: "I think it's important for him [to score] because always all the players struggle in their first season in England.
"When you come from Netherlands it's a different level of competition and in the end he wanted to leave and he decided to go to Turkey, and we wish him all the best and we are happy if he scored last night. It was really good for him, to try to build again his confidence."
"Here he sometimes played, sometimes didn't play," Pochettino added.
"But you know when you have Harry Kane in your position it's not easy to fight and be motivated every day to try to give your best.
"It was his decision, with the club's decision, to send him on loan but we hope he starts to build his confidence and trust and scores goals."