Jese, who signed for Stoke from Paris Saint-Germain on Wednesday, could be set to make his league berth against the Gunners on Saturday.
If selected, he could square off against Kolasinac for the first time since the Bosnia and Herzegovina international tackle torn the Spaniard's knee ligament in 2014.
Rodriguez's injury, by the player's own admission, severely hampered his attempts to live up to his early potential with Los Blancos.
“I have thought about it," he said speaking to Marca in February about his injury.
“And I've never liked comparing myself to anyone, but I think I would be an undisputed starter for Real Madrid. Of that I'm sure.
“You never know, hopefully some day I'll be back. It was the team that birthed me as a footballer — it's like when a mother gives birth, Madrid did that for me."