The star striker was able to hobble off the pitch after he re-injured the ankle that saw him out of action earlier in the season.
But Kane was seen with crutches and a protective boot after the match suggesting that perhaps the problem is quite serious.
"Now we have to wait, we will assess it tomorrow.
"It's difficult. We hope it's not a big issue but it looks a similar situation as his previous injury. We hope it's not a big issue. I'm sure it will be difficult to play against Southampton next weekend.
"Of course I'm sad about Harry's injury but we have to find a solution. When you lose a player like Harry you will miss him.
"Harry is one of the best strikers in England but we can't cry."