Tottenham Hotspur will make changes to their starting line-up for Tuesday night's EFL Cup clash with Liverpool.

Spurs head to Anfield for the fourth round of the league cup and will be taking a different looking squad according to manager Mauricio Pochettino.

Summer signing Moussa Sissoko is set to be suspended for three matches stemming from an incident at AFC Bournemouth on the weekend which compounds the injury absences of Toby Alderweireld and Harry Kane.

Pochettino also confirmed that Michel Vorm will start in goals ahead of captain Hugo Lloris who has started 10 times this season after a heavy schedule with France at Euro2016.

"It's difficult now because Sissoko was in our plans to play, and we don't have Toby or Harry," Pochettino said.

"It's true that tomorrow we will play Michel Vorm. I can confirm that.

"Hugo Lloris is one of the best but he is not a machine. Michel is a very good keeper, as is Pau Lopez and the younger two as well."

Pochettino also suggested that Georges-Kevin N'Koudou, who arrived from Marseille in August, may start for the first time for the North Londoners.

"Maybe [N'Koudou will start too]. I am thinking that maybe I will give him the opportunity to start the game," he added.