Defoe had to be helped off after injuring ankle ligaments in yesterday's Prem win at West Brom.
AVB insisted: "We have enough to get us through. We create a lot in terms of attacking football.
"Remember there was a team who were world champions that play without a striker. You just have to adapt to it in the best way you can.
"We create a lot as a team. Our goals come from different sources and again Bale has done the business."