Southampton have sacked manager Nigel Adkins after two-and-a-half years in charge and appointed Argentine Mauricio Pochettino as manager, reports BBC Sport.
The 40 year old will take charge against Everton on Monday.
The Argentine left Spanish side Espanyol in November and will take charge of training on Saturday for the first time.
"Whilst we acknowledge the contribution Nigel has made during the past two years, for the club to progress and achieve our long-term targets a change was needed.
"Mauricio is a well-respected coach of substantial quality who has gained a reputation as an astute tactician and excellent man manager. I have every confidence that he will inspire our talented squad of players to perform at the highest possible level."
Pochettino said: "This is the kind of opportunity that any coach would relish. Southampton is a club with great heritage, and an even more exciting future.
"There is a clear vision to take the club to a new era of sustained success in the Premier League, and beyond, which I'm delighted to be part of."