Saints had 25 shots over the course of the match, leading manager Mauricio Pochettino to change tack after previously saying "statistics are evil".
"I do like statistics today, I do like them today to justify the defeat," the Argentinian said.
"I am very disappointed with the defeat today. I thought we fully deserved to get something more from that game.
"We had full control in the game and that even led us to go 1-0 up. It is clear that the 1-1 goal came from an offside position and that was unlucky for us.
"Then the team struggled to recover from going 2-1 down and that made everything quite difficult for us as well.
"In the second half we created many good chances and were unlucky not to get the 2-2, which actually changed the game.
"Overall today, I thought we were quite unlucky with the refereeing decisions and to have not scored more goals."
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