Southampton boss Nigel Adkins admits an injury concern for big money signing Gaston Ramirez.
The winger missed their 2-2 draw with Fulham yesterday.
"Gaston's got a similar thing with a dead leg picked up in training on Thursday, but that was quite a serious one," said Adkins.
"The muscle swelled up very much because there was nowhere for the blood to go so there was a lot of pressure on his thigh.
"He has had to have a couple of days in hospital to try and relieve the pressure so obviously he is not going to go and join the Uruguayan team over the international break.